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Papers of the Week
Neurofilament light chain is elevated in patients with newly diagnosed idiopathic intracranial hypertension: A prospective study.
Authors
Svart K, Korsbæk JJ, Jensen RH, Parkner T, Knudsen CS, Hasselbalch SG, Hagen SM, Wibroe EA, Molander LD, Beier DAbstract
Idiopathic intracranial hypertension is a secondary headache disorder potentially causing visual loss. Neurofilament light chain is a candidate, prognostic biomarker, but further studies of neuronal biomarkers are needed. Our objective was to investigate neurofilament light chain in cerebrospinal fluid (cNfL) and plasma (pNfL), amyloid-beta 42 (Aβ-42), total-tau and phosphorylated-tau in cerebrospinal fluid in new-onset idiopathic intracranial hypertension.