I am a
Home I AM A Search Login

Papers of the Week

Papers: 13 Jan 2024 - 19 Jan 2024

2024 Feb 01

Anesth Analg




Multicenter Population Pharmacokinetics of Fentanyl in Neonatal Surgical Patients Using Dried Blood Spot Specimen Collection Demonstrates Maturation of Elimination Clearance.


Rzasa Lynn RS, Henthorn TK, Zuk J, Hammer GB, Drover DR, Levy RJ, Maxwell LG, Sadhasivam S, Suresh S, Galinkin JL


Fentanyl is widely used for analgesia and sedation in neonates, but pharmacokinetic (PK) analysis in this population has been limited by the relatively large sample volumes required for plasma-based assays.