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Papers of the Week

Papers: 3 Feb 2024 - 9 Feb 2024


Curr Res Pharmacol Drug Discov



Long-term effects of neonatal pain and sucrose treatment.


Nuseir K, Alzoubi KH, Altarifi A, Kassab M, Khabour OF, Al-Ghraiybah NF, Obiedat R


In neonatal intensive care units, applying sucrose solution for analgesia is now a routine treatment for mild procedural pain. Studies of animal and human infants provide clear evidence of benefits in the short term, but few studies have investigated the long term benefits. Thus, we determined whether sucrose could ameliorate painful stimulation during infancy in Sprague-Dawley rats and also explored the long-term effects of repeated sucrose administration during infancy. Female and male rats were included to investigate sex-related differences.