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Papers of the Week
Expression of miR-155 in monocytes of people with migraine: association with phenotype, disease severity and inflammatory profile.
Authors
Greco R, Bighiani F, Demartini C, Zanaboni A, Francavilla M, Facchetti S, Vaghi G, Allena M, Martinelli D, Guaschino E, Ghiotto N, Bottiroli S, Corrado M, Cammarota F, Antoniazzi A, Mazzotta E, Pocora MM, Grillo V, Sances G, Tassorelli C, De Icco RAbstract
miR-155 is involved in the generation and maintenance of inflammation and pain, endothelial function and immune system homeostasis, all functions that are relevant for migraine. The present study aims to assess the levels of miR-155 in migraine subtypes (episodic and chronic) in comparison to age- and sex-matched healthy controls.