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Papers of the Week
Effects of oral morphine on experimentally evoked itch and pain: a randomized, double-blind, placebo-controlled trial.
Authors
Okutani H, Lo Vecchio S, Ammitzbøll N, Drewes AM, Arendt-Nielsen LAbstract
Pain and itch share similar neuronal networks; hence, it is difficult to explain why opioids can relieve pain but provoke itching. The present human volunteer study aimed to investigate the similarities and differences in responses to experimentally provoked pain and itching to explore the underlying fundamental mechanisms.