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Papers of the Week


Papers: 3 Feb 2024 - 9 Feb 2024


2024 Feb 07


Neuron


38330897


112


3

Does high-frequency stimulation of sensory axons break the causal link between pain relief and paresthesia?

Authors

Rogers ER, Lempka SF, Capogrosso M

Abstract

Neurostimulation produces unnatural cutaneous sensations with potent analgesic effects in pain syndromes. In this issue of Neuron, Sagalajev et al. demonstrate that these sensations are an epiphenomenon and explain how high-frequency stimulation can provide analgesia without these unnecessary sensations.