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Papers of the Week


Papers: 8 Apr 2023 - 14 Apr 2023

RESEARCH TYPE:
Basic Science, Methodology


Animal Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Inflammation/Inflammatory, Neuropathic Pain


2023 Apr 12


Br J Pharmacol


37050867

Chronic alcohol induced mechanical allodynia by promoting neuroinflammation: a mouse model of alcohol-evoked neuropathic pain.

Authors

Borgonetti V, Roberts AJ, Bajo M, Galeotti N, Roberto M

Abstract

Unrelieved chronic pain is considered a key factor contributing to the maintenance of alcohol use disorder (AUD). The mechanisms responsible for chronic pain associated with chronic alcohol consumption are still unknown. Thus, our goal was to evaluate the development of chronic pain in a mouse model of alcohol dependence and investigate the role of neuroinflammation in this chronic condition.