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Papers of the Week
Calcitonin Gene-Related Peptide Monoclonal Antibodies: Key Lessons from Real-World Evidence.
Authors
Orlando B, Egeo G, Aurilia C, Fiorentini G, Barbanti PAbstract
The advent of monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway has transformed the management of migraine, offering newfound optimism for clinicians and individuals with episodic migraine (EM) and chronic migraine (CM). While randomized controlled trials (RCTs) have provided crucial insights into the effectiveness and safety profiles of these treatments, their translation into real-world clinical practice remains a challenge.