Browse by Audience
Skip to content
Papers of the Week
Biomarkers reflecting disturbed gut barrier under treatment with TNF inhibitors in radiographic axial spondyloarthritis.
Authors
Rademacher J, Torgutalp M, Hempel CM, Proft F, Haibel H, Protopopov M, Spiller L, Poddubnyy D, Rios Rodriguez VAbstract
The objective of this study is to investigate lipopolysaccharid-binding protein (LBP), zonulin and calprotectin as markers of bacterial translocation, disturbed gut barrier and intestinal inflammation in patients with radiographic axial spondyloarthritis (r-axSpA) during tumour necrosis factor inhibitor (TNFi) therapy and to analyze the association between disease activity, response to treatment and biomarker levels.