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Papers of the Week

2023 Mar

Am J Ophthalmol Case Rep


Minimally invasive corneal neurotization for neurotrophic keratopathy: The potential effect of age, denervation chronicity and lesion location.


Ting DSJ, Pradhan SP, Barnes E, Ahmed OA, Figueiredo FC
Am J Ophthalmol Case Rep. 2023 Mar; 29:101804.
PMID: 36718433.


Neurotrophic keratopathy (NK) is an uncommon but challenging clinical condition characterized by altered corneal nerves and sensation leading to corneal damage. Corneal neurotization, a surgical technique that aims to "re-innervate" the cornea, has gained increasing popularity in view of the potential to permanently improve or even restore the normal corneal sensation. In this study, we aimed to report the outcomes of two cases of NK that underwent indirect minimally invasive corneal neurotization (MICN) with a sural nerve autograft, and to provide plausible explanations for the observed clinical outcomes.