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Papers: 7 Jan 2023 - 13 Jan 2023

2023 Jan 11

J Vet Intern Med

SCN9A variant in a family of mixed breed dogs with congenital insensitivity to pain.


Gutierrez-Quintana R, Christen M, Faller KME, Guevar J, Jagannathan V, Leeb T
J Vet Intern Med. 2023 Jan 11.
PMID: 36630088.


Congenital insensitivity to pain (CIP) and hereditary sensory and autonomic neuropathies (HSANs) are a rare group of genetic disorders causing inability to feel pain. Three different associated variants have been identified in dogs: 1 in Border Collies, 1 in mixed breed dogs, and 1 in Spaniels and Pointers.