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Papers of the Week
Water extract of Notopterygium incisum alleviates cold allodynia in neuropathic pain by regulation of TRPA1.
Abstract
Neuropathic pain can be debilitating and drastically affects the quality of life of those patients suffering from this condition. The Chinese herb Notopterygium incisum Ting ex H.T. Chang has long been used to disperse "cold". One under examined clinical feature of neuropathic pain is sensitivity to cold. Patients with neuropathic pain or arthritis usually describe a worsening of symptoms during the winter.