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Papers of the Week

Papers: 31 Dec 2022 - 6 Jan 2023

2022 Dec 28

J Neurosci Methods

A novel thermoelectric device integrated with a psychophysical paradigm to study pain processing in human subjects.


Caston RM, Davis TS, Smith EH, Rahimpour S, Rolston JD
J Neurosci Methods. 2022 Dec 28:109780.
PMID: 36586439.


Cerebral projections of nociceptive stimuli are of great interest as targets for neuromodulation in chronic pain. To study cerebral networks involved in processing noxious stimuli, researchers often rely on thermo-nociception to induce pain. However, various limitations exist in many pain-inducing techniques, such as not accounting for individual variations in pain and trial structure predictability.