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Papers: 24 Dec 2022 - 30 Dec 2022

2022 Dec 25


Is ketamine infusion effective and safe as an adjuvant of sedation in the PICU? Results from the Ketamine Infusion Sedation Study (KISS).


Tessari A, Sperotto F, Pece F, Pettenuzzo G, Porcellato N, Poletto E, Mondardini M C, Pettenazzo A, Daverio M, Amigoni A
Pharmacotherapy. 2022 Dec 25.
PMID: 36567489.


We aimed to evaluate the efficacy and safety of ketamine in ensuring comfort and sparing conventional drugs when used as an adjuvant for analgesia and sedation in the Pediatric Intensive Care Unit (PICU) as a continuous infusion (≥12 hours).