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Papers of the Week


Papers: 24 Dec 2022 - 30 Dec 2022


2022 Dec 25


Pharmacotherapy

Is ketamine infusion effective and safe as an adjuvant of sedation in the PICU? Results from the Ketamine Infusion Sedation Study (KISS).

Authors

Tessari A, Sperotto F, Pece F, Pettenuzzo G, Porcellato N, Poletto E, Mondardini M C, Pettenazzo A, Daverio M, Amigoni A
Pharmacotherapy. 2022 Dec 25.
PMID: 36567489.

Abstract

We aimed to evaluate the efficacy and safety of ketamine in ensuring comfort and sparing conventional drugs when used as an adjuvant for analgesia and sedation in the Pediatric Intensive Care Unit (PICU) as a continuous infusion (≥12 hours).