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Papers of the Week


2022 Dec 24


BMC Musculoskelet Disord


23


1

Randomized, double-blind, noninferiority study of diclofenac diethylamine 2.32% gel applied twice daily versus diclofenac diethylamine 1.16% gel applied four times daily in patients with acute ankle sprain.

Authors

Yin F, Ma J, Xiao H, Ao R, Zhang F, Li W, Wang W, Zeng P, Lu T, Bariguian Revel F, Araga M, Patel S, Moreira S, Zhang J, Zhang W
BMC Musculoskelet Disord. 2022 Dec 24; 23(1):1125.
PMID: 36566202.

Abstract

Diclofenac diethylamine (DDEA) gel has demonstrated efficacy for treatment of ankle sprains in both the 1.16% four-times-daily (QID) and 2.32% twice-daily (BID) formulations. The objective of this study was to compare, for the first time, the efficacy of DDEA 2.32% gel BID and DDEA 1.16% gel QID.