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Papers of the Week

2022 Dec 16

J Ethnopharmacol

Efficacy and safety of add-on Viola odorata L. in the treatment of COVID-19: A randomized double-blind controlled trial.


Adel Mehraban M S, Shirzad M, Mohammad Taghizadeh Kashani L, Ahmadian-Attari M M, Safari A A, Ansari N, Hatami H, Kamalinejad M
J Ethnopharmacol. 2022 Dec 16:116058.
PMID: 36535329.


Severe acute respiratory syndrome (SARS) due to the novel coronavirus has become the highest priority that threatens human health. This situation demands widespread vaccination and the innovation of new therapeutic methods. Despite drug discoveries, the need for approving new medicaments is felt because of adverse effects and lack of efficacy. Several medicinal plants including Viola odorata L. are recommended in traditional Persian medicine for alleviating respiratory infection symptoms. Recent studies showed anti-inflammatory, antioxidant, anti-asthmatic, antitussive, analgesic, and antibacterial activities of sweet violet. These enhance respiratory functions, reduce pulmonary inflammation, and decline mucous membrane edema. This study aimed to evaluate the efficacy of sweet violet syrup in alleviating the manifestations of COVID-19 infection.