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Papers of the Week

2022 Oct 05

Turk Neurosurg

The Matrix Metalloproteinase Inhibitor Batimastat Reduces Epidural Fibrosis After Laminectomy in Rats.


Yurtal Z, Ozkan H, Kutlu T, Deveci M Z, Urfali B, Urfali S
Turk Neurosurg. 2022 Oct 05.
PMID: 36482856.


Epidural fibrosis is a major cause of postlaminectomy syndrome or "failed back surgery syndrome," which may occur after spinal surgical interventions. It reduces the quality of life, and is characterized by persistent back/low back pain and radicular leg pain. The aim of this experimental study was to investigate the efficacy of locally applied batimastat after laminectomy in preventing postoperative epidural fibrosis.