I am a
Home I AM A Search Login

Papers of the Week


2022 Oct 05


Turk Neurosurg

The Matrix Metalloproteinase Inhibitor Batimastat Reduces Epidural Fibrosis After Laminectomy in Rats.

Authors

Yurtal Z, Ozkan H, Kutlu T, Deveci M Z, Urfali B, Urfali S
Turk Neurosurg. 2022 Oct 05.
PMID: 36482856.

Abstract

Epidural fibrosis is a major cause of postlaminectomy syndrome or "failed back surgery syndrome," which may occur after spinal surgical interventions. It reduces the quality of life, and is characterized by persistent back/low back pain and radicular leg pain. The aim of this experimental study was to investigate the efficacy of locally applied batimastat after laminectomy in preventing postoperative epidural fibrosis.