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Clin Cosmet Investig Dermatol


SAPHO Syndrome with Palmoplantar Pustulosis as the First Manifestation Successfully Treated with Adalimumab.


Yang Q, Xiang T, Wu Y, Ye E, He B, Bu Z
Clin Cosmet Investig Dermatol. 2022; 15:2547-2554.
PMID: 36466944.


Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is an acronym for synovitis, pustulosis, acne, hyperostosis, and osteitis, and clinically manifests as dermatological and musculoskeletal damage. Two major manifestations that co-occur in a single patient are rare.