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Papers of the Week

Papers: 19 Nov 2022 - 25 Nov 2022

2022 Nov-Dec

Pain Rep



Using evoked compound action potentials to quantify differential neural activation with burst and conventional, 40 Hz spinal cord stimulation in ovines.


Dinsmoor DA, Usoro JO, Barka ND, Billstrom TM, Litvak LM, Poree LR
Pain Rep. 2022 Nov-Dec; 7(6):e1047.
PMID: 36398199.


Unlike conventional dorsal spinal cord stimulation (SCS)-which uses single pulses at a fixed rate-burst SCS uses a fixed-rate, five-pulse stimuli cluster as a treatment for chronic pain; mechanistic explanations suggest burst SCS differentially modulate the medial and lateral pain pathways vs conventional SCS. Neural activation differences between burst and conventional SCS are quantifiable with the spinal-evoked compound action potential (ECAP), an electrical measure of synchronous neural activation.