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Papers of the Week


2022 Nov 02


J Hepatol

Hepatic and renal improvements with FXR agonist vonafexor in individuals with suspected fibrotic NASH.

Authors

Ratziu V, Harrison SA, Loustaud-Ratti V, Bureau C, Lawitz E, Abdelmalek M, Alkhouri N, Francque S, Girma H, Darteil R, Couchoux H, Wolf M, Sanyal A, Vonderscher J, Scalfaro P
J Hepatol. 2022 Nov 02.
PMID: 36334688.

Abstract

The LIVIFY trial investigated the safety, tolerability, and efficacy, of Vonafexor, a second-generation, non-bile acid farnesoid X receptor agonist in patients with suspected fibrotic non-alcoholic steatohepatitis (NASH).