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Papers of the Week

Papers: 22 Oct 2022 - 28 Oct 2022

2022 Oct

Pain Physician



Exercise Facilitates the M1-to-M2 Polarization of Microglia by Enhancing Autophagy via the BDNF/AKT/mTOR Pathway in Neuropathic Pain.


Bai J, Geng B, Wang X, Wang S, Yi Q, Tang Y, Xia Y
Pain Physician. 2022 Oct; 25(7):E1137-E1151.
PMID: 36288601.


In neuropathic pain following peripheral nerve injury, microglia are rapidly activated and accumulated in the spinal cord. Physical exercise can alleviate neuropathic pain. However, the exact mechanism underlying this analgesic effect is not fully understood.