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Papers of the Week


Papers: 22 Oct 2022 - 28 Oct 2022


2022 Oct


Pain Physician


25


7

Exercise Facilitates the M1-to-M2 Polarization of Microglia by Enhancing Autophagy via the BDNF/AKT/mTOR Pathway in Neuropathic Pain.

Authors

Bai J, Geng B, Wang X, Wang S, Yi Q, Tang Y, Xia Y
Pain Physician. 2022 Oct; 25(7):E1137-E1151.
PMID: 36288601.

Abstract

In neuropathic pain following peripheral nerve injury, microglia are rapidly activated and accumulated in the spinal cord. Physical exercise can alleviate neuropathic pain. However, the exact mechanism underlying this analgesic effect is not fully understood.