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Papers of the Week


2022 Sep 30


J Allergy Clin Immunol

Allergen Immunotherapy for Atopic Dermatitis: A Systematic Review and Meta-Analysis of Benefits and Harms.

Authors

Yepes-Nuñez J J, Guyatt GH, Gómez-Escobar L G, Pérez-Herrera LC, Chu A, Ceccaci R, Acosta-Madiedo A S, Wen A, Moreno-López S, MacDonald M, Barrios M, Chu X, Islam N, Gao Y, Wong MM, Couban R, Garcia E, Chapman E, Oykhman P, Chen L, et al.
J Allergy Clin Immunol. 2022 Sep 30.
PMID: 36191689.

Abstract

Atopic dermatitis (AD, eczema) is driven by a combination of skin barrier defects, immune dysregulation, and extrinsic stimuli (eg. allergens, irritants, microbes). The role of environmental allergens (aeroallergens) in triggering AD remains unclear.