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Papers of the Week


2022 Aug 30


Intern Med

Temporal Arteritis Caused by Tertiary Syphilis.

Authors

Katayama K, Ishizuka K, Tawara J, Kaji Y, Komuta M, Hayashi Y, Gomi H, Akahane M, Ohira Y
Intern Med. 2022 Aug 30.
PMID: 36047113.

Abstract

A 77-year-old man arrived at our hospital with bilateral shoulder pain persisting for several months and headache for 1 month. Giant cell arteritis with polymyalgia rheumatica was suspected. However, considering his medical history of testing positive for syphilis, we submitted a sample for a syphilis serology test, which yielded positive results. The Treponema pallidum hemagglutination assay of cerebrospinal fluid was positive, and a temporal artery biopsy revealed vasculitis, confirming the diagnosis of tertiary syphilis. He was successfully treated for two weeks with penicillin G infusions. Symptoms reminiscent of giant cell arteritis and polymyalgia rheumatica may reveal syphilis, which is called the "great imitator."