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Papers of the Week

2022 Jul 19

J Neurol Sci


Reversible cerebral artery constriction accompanied with stroke-like episode in MELAS: A case series.


Zhao Y, Yu X, Ji K, Lin Y, Xu X, Wang W, Yan C
J Neurol Sci. 2022 Jul 19; 441:120345.
PMID: 35940028.


The pathophysiology of stroke-like episode (SLE) in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) was uncertain, though mitochondrial metabolic crisis of cortical neurons and mitochondrial proliferation in small vessels of brain have been considered. However, the involvement of major cerebral vessels was debated. We aimed to investigate whether major cerebral vessels participate in SLE.