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Papers of the Week

2022 Jul

Ann Med Surg (Lond)


Right arm weakness and mouth deviation as a presentation of Primary Angiitis of the Central Nervous System treated with rituximab: A case-report.


Sarhan F M, Al-Jasim A, Alaraj R S, Abedalkhader S F, Ghanim Z
Ann Med Surg (Lond). 2022 Jul; 79:104040.
PMID: 35860065.


Primary Angiitis of the Central Nervous System (PACNS) is a rare form of vasculitis that solely affects the Central Nervous System (CNS). Its presentation varies widely from a simple headache to a stroke-like presentation. PACNS management is divided into an induction phase, which includes corticosteroids, cyclophosphamide and rituximab, and a maintenance phase which includes: methotrexate, mycophenolate mofetil, rituximab and azathioprine.