Papers of the Week

There is a lack of evidence about how Health-related Quality of Life (HRQoL), including psychosocial factors, might affect donation-related experiences and clinical markers in the context of hematopoietic stem cell (HSC) donation. The broader literature suggests that psychological factors, including anxiety and depression, are associated with higher levels of inflammatory burden leading to poorer post-procedural outcomes including longer hospital stays and increased pain perception. In this study, we aimed to evaluate whether pre-donation HRQoL markers predict toxicity profile and stem cell yield following PBSC donation in healthy donors.