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Papers of the Week

Papers: 28 May 2022 - 3 Jun 2022

2022 Jun 01

Pain Manag

Management of chronic non-cancer pain: a framework.


Nadeau SE, Lawhern RA
Pain Manag. 2022 Jun 01.
PMID: 35642546.


Since publication of the CDC 2016 Guideline, opioid-related mortality in the USA has doubled and a crisis has developed among the 15-20 million Americans with chronic, moderate-to-severe, noncancer pain. Our aim was to develop a comprehensive alternative approach to management of chronic pain. Analytic review of the clinical literature. Published science provides a solid framework for the management of chronic non-cancer pain, detailed here, even as it leaves many knowledge gaps, which we fill with insights from clinical experience. There is a sufficient basis in science and in clinical experience to achieve adequate control of chronic pain in nearly all patients in a way that adequately balances benefits and potential harms.