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Papers of the Week

Papers: 21 May 2022 - 27 May 2022

2022 May 23

Eur J Pain

Altered prefrontal-striatal theta-band oscillatory dynamics underlie working memory deficits in neuropathic pain rats.


Cardoso-Cruz H, Laranjeira I, Monteiro C, Galhardo V
Eur J Pain. 2022 May 23.
PMID: 35603472.


Prelimbic medial prefrontal cortex (PL-mPFC) and nucleus accumbens core region (NAcc) play an important role in supporting several executive cognitive mechanisms, such as spatial working-memory (WM). Recently, this circuit has been also associated with both sensory and affective components of pain. However, it is still unclear whether this circuit is endogenously engaged in neuropathic pain-related cognitive dysfunctions.