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Papers of the Week


2022 May 19


Acta Neurol Belg

SMART syndrome: a case report.

Authors

Bozkurt S, Toprak B, Yıldırım HÇağrı, Parlak Ş, Güven D C, Kertmen N, Karlı Oğuz K, Dizdar Ö
Acta Neurol Belg. 2022 May 19.
PMID: 35587312.

Abstract

Stroke-like migraine attacks after radiation therapy (SMART) syndrome, is a late complication of brain radiotherapy (1). Symptoms are commonly subacute in onset and involve migraine type of headache, seizures, focal neurologic deficits (2). Magnetic resonance imaging (MRI) findings are usually unilateral and posterior predominant cortical-subcortical hyperintensity, swelling and prominent gyriform (cortical and leptomeningeal) gadolinium enhancement in the areas of the brain that underwent irradiation with or without diffusion restriction (1). There is no standard treatment protocol for SMART syndrome. Antiepileptics and corticosteroids are commonly used drugs.