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Papers of the Week

2021 Nov-Dec

J Conserv Dent



Anti-inflammatory efficacy of petasin-incorporated zinc oxide eugenol sealer – An zebrafish study.


Vinola SMJ, Karthikeyan K, Sharma A, Sudheshna S, Sekar M
J Conserv Dent. 2021 Nov-Dec; 24(6):539-543.
PMID: 35558677.


The eugenol from zinc oxide eugenol (ZnOE) sealer tends to diffuse to the periapical region resulting in inflammation. Several modifications of ZnOE sealer have been formulated to minimize the inflammatory potential of the ZnOE sealer. contains petasin which possesses anti-inflammatory property used in treatment of migraine and allergic rhinitis.