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Papers of the Week

Papers: 14 May 2022 - 20 May 2022

2022 May


36 Suppl 1

Astrocyte Reactivity in Female Rats with Persistent Low Back Pain Following Spinal Mobilization.


Lima C R, Avatapally S, Li P, Reed W
FASEB J. 2022 May; 36 Suppl 1.
PMID: 35560929.


Low back pain (LBP) is a physiologically complex and highly disabling condition with poorly understood pathophysiology. Glial reactivity has been reported in patients with chronic LBP and astrocyte reactivity has been suggested as a potential contributor to LBP chronicity. Spinal mobilization (SM) is a non-pharmacological approach with mild to moderate efficacy in treating LBP but physiological mechanisms responsible are unknown.