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Papers of the Week

Papers: 30 Apr 2022 - 6 May 2022

Human Studies

2022 Apr 30

Am J Obstet Gynecol

Migraine and adverse pregnancy outcomes: the nuMoM2b study.


Miller EC, Chau K, Mammadli G, Levine LD, Grobman WA, Wapner R, Bello NA
Am J Obstet Gynecol. 2022 Apr 30.
PMID: 35504328.


Migraine affects 28% of women in their pregnancy-capable years, and is associated with systemic inflammation, endothelial dysfunction, and increased risk of pregnancy-associated thromboembolic events. Migraine history has been associated with adverse pregnancy outcomes (APO) of placental origin, including hypertensive disorders of pregnancy (HDP) and preterm birth (PTB). We tested the hypothesis that self-reported migraine in nulliparous individuals is associated with higher odds of APO.