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Papers of the Week

2022 Feb 11

J Chem Neuroanat

Nerve fiber density differences in the temporal dura mater: an explanation for headache after temporal lobectomy?, An anatomical study.


Sloekers JCT, Herrler A, Hoogland G, Rijkers K, Beckervordersandforth J, van Kuijk SMJ, Schijns OEMG
J Chem Neuroanat. 2022 Feb 11:102082.
PMID: 35158040.


Patients who undergo a temporal lobectomy for drug-resistant epilepsy more frequently complain about postoperative headache compared to patients who undergo a craniotomy in any other region. The pathophysiological mechanism is not well understood. It is hypothesized that a relatively high density of sensory nerve fibers in the temporomesial dura underlies a higher sensitivity to pain upon stimulation. The objective of this study was to address this hypothesis by comparing the nerve fiber density in the temporomesial dura to that in the temporolateral dura.