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Papers of the Week
Different genes may be involved in distal and local sensitisation: a genome-wide gene-based association study and meta-analysis.
Abstract
Neuropathic pain symptoms and signs of increased pain sensitisation in osteoarthritis (OA) patients may explain persistent pain after total joint replacement (TJR). Therefore, identifying genetic markers associated with pain sensitisation and neuropathic-like pain phenotypes could be clinically important in identifying targets for early intervention.