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Papers of the Week

Papers: 11 Dec 2021 - 17 Dec 2021

Human Studies, Pharmacology/Drug Development

2021 Dec 16

Scand J Pain

The association between pain and central nervous system depressing medication among hospitalised Norwegian older adults.


Bjelkarøy M T, Cheng S, Siddiqui T G, Benth J Š, Grambaite R, Kristoffersen E S, Lundqvist C
Scand J Pain. 2021 Dec 16.
PMID: 34913326.


Central nervous system depressant medications (CNSD) including benzodiazepines, z-hypnotics and opioids are regularly prescribed for the older patient. These medications are linked to dependence and associated with severe side effects in some older patients. Consensus recommendations for this group suggest limiting their use. We have recently described a high proportion of long-term CNSD use and dependence among older in-hospital patients. In this study, we aim to investigate factors associated with pain intensity and presentation of pain among older adults with long-term use of CNSDs compared to non-users.