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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Development and Evaluation of a Droplet Digital PCR Assay for 8p23 β-Defensin Cluster Copy Number Determination.

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2021 Jul 29


Mol Diagn Ther


http://www.ncbi.nlm.nih.gov/pubmed/34327613?dopt=Abstract

Development and Evaluation of a Droplet Digital PCR Assay for 8p23 β-Defensin Cluster Copy Number Determination.

Authors

Development and Evaluation of a Droplet Digital PCR Assay for 8p23 β-Defensin Cluster Copy Number Determination.
Wen T, Zhang X, Lippuner C, Schiff M, Stuber F
Mol Diagn Ther. 2021 Jul 29.
PMID: 34327613.

Abstract

It has been proposed that the copy number (CN) variation (CNV) in β-defensin genes (DEFB) on human chromosome 8p23 determines phenotypic differences in inflammatory diseases. However, no method for accurate and easy DEFB CN quantification is yet available.
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