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Papers of the Week

2021 Jun 23

Hum Genomics



Regulatory VCAN polymorphism is associated with shoulder pain and disability in breast cancer survivors.


Mafu TS, September AV, Shamley D
Hum Genomics. 2021 Jun 23; 15(1):36.
PMID: 34162438.


Shoulder morbidity following breast cancer treatment is multifactorial. Despite several treatment- and patient-related factors being implicated, unexplained inter-individual variability exists in the development of such morbidity. Given the paucity of relavant genetic studies, we investigate the role of polymorphisms in candidate proteoglycan genes.