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Papers of the Week

2021 Jun 07

Br J Haematol

Management of a patient with a rare congenital limb malformation syndrome after SARS-CoV-2 vaccine-induced thrombosis and thrombocytopenia (VITT).


A 54-year-old man with a rare congenital limb malformation (left image) presented to the Accident and Emergency department with a 7-day history of worsening headache, bruising and unilateral right calf swelling. There was a strong family history of a rare congenital limb deformity, his mother and his maternal grand-father having the same congenital deformity. Computed tomography (CT) showed an extensive cerebral venous sinus thrombosis and ultrasonography confirmed a concurrent venous thrombosis in the portal vein (right image, filling defect indicated by arrow).