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Papers of the Week

2021 Jan

J Family Med Prim Care



Frequent clinical and radiological manifestations of the Novel SARS-CoV-2: A review article.


Alshoabi S A, Alhazmi FH, Abdulaal OM, Gameraddin MB, Algaberi AK, Hamid AM, Alsultan KD, Alamri AM
J Family Med Prim Care. 2021 Jan; 10(1):122-126.
PMID: 34017713.


Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the novel "severe acute respiratory syndrome coronavirus-2" (SARS-CoV-2) and is rapidly spreading worldwide. This review is designed to highlight the most common clinical features and computed tomography (CT) signs of patients with COVID-19 and to elaborate the most significant signs indicative of COVID-19 diagnosis. This review involved five original articles with both clinical and radiological features of COVID-19 published during Jan and Mar 2020. In this review, the most frequent symptoms of COVID-19 were fever and cough. Myalgia, fatigue, sore throat, headache, diarrhea, and dyspnea were less common manifestations. Nausea and vomiting were rare. Ground-glass opacity (GGO) was the most common radiological finding on CT, and mixed GGO with consolidation was reported in some cases. In addition, elevated C-reactive protein and lymphopenia are the pertinent laboratory findings of COVID-19. CT is an effective and important imaging tool for both diagnosis and follow-up COVID-19 patients with varied features, duration, and course of the disease. Bilateral GGOs, especially in the periphery of the lungs with or without consolidation, are the hallmark of COVID-19.