I am a
Home I AM A Search Login

Papers of the Week

Papers: 8 May 2021 - 14 May 2021

Animal Studies, Pharmacology/Drug Development

2021 May 11

J Neuroinflammation



Capsazepine decreases corneal pain syndrome in severe dry eye disease.


Fakih D, Guerrero-Moreno A, Baudouin C, Réaux-Le Goazigo A, Mélik Parsadaniantz S
J Neuroinflammation. 2021 May 11; 18(1):111.
PMID: 33975636.


Dry eye disease (DED) is a multifactorial disease of the ocular surface accompanied by neurosensory abnormalities. Here, we evaluated the effectiveness of transient receptor potential vanilloid-1 (TRPV1) blockade to alleviate ocular pain, neuroinflammation, and anxiety-like behavior associated with severe DED.