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Papers of the Week

2021 Apr 30

Int J Surg Case Rep


Mixed pancreatic hepatoid carcinoma: A surgical case report and literature review.


Trinh H S, Luong T H, Lai T T, Nguyen T K
Int J Surg Case Rep. 2021 Apr 30; 83:105951.
PMID: 33971555.


Hepatoid carcinoma (HC) is a rare type of malignant tumor that shared similar features of morphology and immunohistochemistry with hepatocellular carcinoma (HCC). Pancreatic HC exists as either pure or mixed type. Mixed pancreatic HC is extremely rare, with only a few cases reported in the literature to date. Because of the rarity of mixed pancreatic HC, its clinical features including incidence, characteristics, and prognosis remain unclear. We herein report a case of a 49-year-old man who was diagnosed with mixed pancreatic HC with neuroendocrine differentiation and was treated with pancreaticoduodenectomy and adjuvant chemotherapy. We also review the existing case reports in literature.