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Papers of the Week

2021 Mar 02

Brain Stimul

Alternate sessions of transcranial direct current stimulation (tDCS) reduce chronic pain in women affected by chikungunya. A randomized clinical trial.


De Souza CG, Pegado R, Costa JF, Morya E, Baptista A, Unal G, Bikson M, Okano AH
Brain Stimul. 2021 Mar 02.
PMID: 33667699.


Thousands of people worldwide have been infected by the chikungunya virus (CHIKV), and the persistence of joint pain symptoms has been considered the main problem. The mechanisms of neuropathic pain include cortical areas. Neuromodulation techniques such as transcranial direct current stimulation (tDCS) act on brain areas involved in the processing of chronic pain. It was previously demonstrated that tDCS for five consecutive days significantly reduced pain in the chronic phase of chikungunya (CHIK).