I am a
Home I AM A Search Login

Papers of the Week

Papers: 17 Oct 2020 - 23 Oct 2020

Human Studies, Pharmacology/Drug Development

2020 Oct 20

Clin J Pain

A Three-Way Crossover Study of Pregabalin, Placebo and the Histamine 3 Receptor Inverse Agonist AZD5213 in Combination with Pregabalin in Subjects with Painful Diabetic Neuropathy and Good Pain-Reporting Ability.


In this study, patients with painful diabetic neuropathy (PDN) were trained using an experimental pain paradigm in an attempt to enroll a subset of patients who are "pain connoisseurs" and therefore more able to discriminate between active and placebo treatments.