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Papers of the Week


Papers: 26 Sep 2020 - 2 Oct 2020


Animal Studies


2021


Methods Mol Biol


2201

Mechanical Nociception in Mice and Rats: Measurement with Automated von Frey Equipment.

Authors

Campana G, Rimondini R
Methods Mol Biol. 2021; 2201:195-198.
PMID: 32975800.

Abstract

von Frey hairs are important tools for the study of mechanisms of cutaneous stimulation-induced sensory input. Mechanical force is exerted via application of a particular hair to the cutaneous receptive field until buckling of the hair occurs. The most commonly used von Frey filaments are productive in evaluating behavioral responses of neuropathic pain in preclinical and clinical research. To reduce the potential experimenter bias, automated instruments are being developed for behavioral assessment.