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Papers: 12 Sep 2020 - 18 Sep 2020

2020 Sep 10

BMJ Open



Predictors of chronic pain and level of physical function in total knee arthroplasty: a protocol for a systematic review and meta-analysis.


Olsen U, Lindberg M F, Denison E M-L, Rose C J, Gay C L, Aamodt A, Brox J I, Skare Ø, Furnes O, Lee KA, Lerdal A
BMJ Open. 2020 Sep 10; 10(9):e037674.
PMID: 32912987.


One in five patients undergoing total knee arthroplasty (TKA) experience unchanged or worse pain and physical function 1 year after surgery. Identifying risk factors for unfavourable outcomes is necessary to develop tailored interventions to minimise risk. There is a need to review more current literature with updated methodology that addresses the limitations of earlier systematic reviews and meta-analyses. We present a Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols compliant protocol for a systematic review and meta-analysis of predictors of chronic pain and impaired function after TKA.