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Evid Based Complement Alternat Med


Therapeutic Effect of and Hederagenin on Chronic Neuropathic Pain of Chronic Constriction Injury of Sciatic Nerve Rats Based on KEGG Pathway Prediction and Experimental Verification.


Hederagenin is one of the main components of , and is one of the ingredients of Danggui Sini decoction. To explore whether and hederagenin can alleviate mechanical pain, thermal hyperalgesia, and cold pain at the same time, we comprehensively investigated the effects of two drugs on the levels of p38 MAPK phosphorylation, TRP proteins, and IL1, IL6, and TNF- in serum.