I am a
Home I AM A Search Login

Papers of the Week


2020 Jun 23


J Ethnopharmacol

In vitro and in vivo anti-inflammatory effects of different extracts from Epigynum auritum through down-regulation of NF-κB and MAPK signaling pathways.

Authors

Yang M, Wang Y, Patel G, Xue Q, Singor Njateng G S, Cai S, Cheng G, Kai G
J Ethnopharmacol. 2020 Jun 23:113105.
PMID: 32590114.

Abstract

Epigynum auritum has been historically used as a "dai" or traditional medicine for the treatment of inflammation, swelling and severe pain during injury; these may reduce risk of disease and lead to healthier aging. Apart from this, Epigynum auritum extract was also used in arhritis treatment which is also a type of inflammation. Previous phytochemical studies of E. auritum revealed that steroids are main characteristic components with a number of biological activities (especially immunosuppressive and anti-inflammatory activity) Nevertheless, the underlying mechanism of the E. auritum on inflammatory diseases is still unresolved.